Precision Medicine: Personalized Drug-Effect Treatment

Three pills lined up in a row

Morehouse School of Medicine logo
Children's Healthcare of Atlanta logo
Grady Health System logo

Care Coordination Institute

Northside
Anesthesiologists

PATIENT-CENTERED CARE CLUSTER – PROJECT 11-05161.GIT

Precision Medicine: Personalized Drug-Effect Treatment

Description

The term “personalized medicine” is often described as providing “the right patient with the right drug at the right dose at the right time.” More broadly, personalized medicine (also known as precision medicine) may be thought of as the tailoring of medical treatment to the individual characteristics, needs, and preferences of a patient during all stages of care, including prevention, diagnosis, treatment, and follow-up. This project focuses on evidence-based approach where treatment design and management is personalized. Drug-drug interactions and side effects will be modeled to reduce unnecessary drugs and minimize negative effect, particularly for the treatment of chronic diseases where multiple conditions exist and multiple drugs are used. The objective of this study covers both the clinical visits and a patient-home-centric approach to optimize the outcome and sustained health of individual patients.

How is this different from related research?

This project focuses on personalized treatment design and will accommodate potential co-existing multiple conditions, rather than a single disease. Evidence will be uncovered from real-patient data to establish the relationship between drug prescription and patient response. A treatment design model based on math programming will reduce the negative effect of individual provider’s subjectivity on decision making process in prescribing treatments and drug therapy. The project will bring together multi-team of providers to identify guidelines of multiple disease treatment. It provides an analytic tool that assists doctors to perform patient-centered complex treatment management.

Value Proposition

  • Formulate a predictive drug effect model characterizing personalized drug response
  • Maximize the success of treatment outcome while avoiding overdosing and minimizing drug-drug interactions through treatment plan personalized and designed for individual patient for his/her conditions
  • Establish outcome evaluation and cost effectiveness of resulting optimized individualized treatment plans (compared to current clinical plans)
Morehouse School of Medicine logo
Children's Healthcare of Atlanta logo

Northside
Anesthesiologists

Grady Health System logo

Care Coordination Institute